Michael J Fox has it, the late Muhammad Ali had it, Billy Connolly has it and more than 100,000 Australians have it. About 30 new cases of Parkinson's disease are being diagnosed every day in this country. If you want to avoid adding your name to that list there is one thing you should do. Don't eat seed oils.
James Parkinson, surgeon, geologist and palaeontologist first described what we now call Parkinson's disease in his paper on shaking palsy in 1817. He was born on April 11, 1755, which is why April 11 is World Parkinson's Day. Dr Parkinson described a condition which caused involuntary tremors when a limb is at rest, rigidity, slowness of movement and a propensity to bend forwards and slow gait when walking. There was no known cause or cure.
We now know that Parkinson's is caused by the death of cells in our pars compacta –the part of our brain which controls motor function (the Substantia nigra pars compacta if you want to get all technical). That part of the brain is a central switching room for movement, attention, learning and reward-seeking (which makes sure we keep eating and having sex).
The pars compacta exerts its control using dopamine. When everything is working well, our bodies are inhibited from moving by the part of our brain which contains the pars compacta (the basal ganglia for Latin freaks). When we decide to move something (our eyes or limbs etc), the pars compacta squirts out dopamine to take the brakes off.
If the neurons responsible for producing the dopamine are damaged, Parkinson's disease is the result. Our brain is pretty durable, because we lose around 50% of our dopamine manufacturing neurons before there are any symptoms. But once they are gone, these neurons are gone forever. As the numbers decrease, a Parkinson's sufferer has to exert greater and greater effort to produce movement.